Do not take this medication with any of the following:
-Aromatase inhibitors like aminoglutethimide, anastrozole, exemestane, letrozole, testolactone
This medication may also interact with the following:
-Antibiotics used to treat tuberculosis like rifabutin, rifampin and rifapentine
-Raloxifene or tamoxifen
-Warfarin

They need to know if you have any of these conditions:
-Abnormal vaginal bleeding
-Blood vessel disease or blood clots
-Cancer, such as breast, cervical, endometrial, ovarian, liver, or uterine cancer
-Dementia
-Diabetes
-Gallbladder disease
-Heart disease or recent heart attack
-High blood pressure
-High cholesterol
-High levels of calcium in your blood
-Hysterectomy
-Kidney disease
-Liver disease
-Lupus
-Migraine headaches
-Protein C or S deficiency
-Stroke
-Tobacco use
-Thyroid disease
-An unusual or allergic reaction to estrogens, soy, other medications, foods, dyes, or preservatives
-Pregnant or trying to get pregnant
-Breastfeeding

Visit your care team for regular checks on your progress. You will need a regular breast and pelvic exam. You should also discuss the need for regular mammograms with your care team, and follow their guidelines.
This medication can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your care team if you feel you are retaining fluid.
If you may be pregnant, stop taking this medication right away and contact your care team.
Talk to your care team if you use tobacco products. Changes to your treatment plan may be needed. Tobacco increases the risk of getting a blood clot or having a stroke while you are taking this medication. This risk is higher if you are 35 years or older.
If you wear contact lenses and notice visual changes, or if the lenses begin to feel uncomfortable, consult your eye care specialist.
If you are going to have elective surgery, tell your care team you are taking this medication. You may need to stop taking this medication before the surgery.
This medication can transfer from your body to others. If a person or pet comes in contact with the medication, they may have serious side effects. If you cannot avoid skin-to-skin contact, cover the application site with clothing. If accidental contact happens, wash the skin of the person or pet right away with soap and water.

Keep out of the reach of children and pets.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medication after the expiration date.