How To Use Amantadine

Amantadine comes in the form of an immediate-release oral tablet, capsule, and oral solution. It also comes as an extended-release tablet and capsule. The immediate-release capsules, tablets, and liquid are usually taken 1-2 times a day by mouth. The extended-release capsules are usually taken once a day at bedtime, and the ER tablets are usually taken once a day in the morning. You should try to take your medicine at the same time(s) every day.

Read the prescription label and follow your doctor’s dosing instructions carefully. Use amantadine exactly as directed. Do not take a higher or lower dose of this medicine or take it more or less frequently than your doctor prescribes.

Do not crush, chew, or split the extended-release capsules or tablets. However, if you have trouble swallowing pills, you can open the ER capsules and sprinkle the contents on some soft food like applesauce. Do not chew the mixture or store it for later use. Eat the mixture right away and swallow it without chewing.

Your doctor may start you on a low dose of amantadine and increase the dose gradually. Do not stop amantadine therapy without talking to your doctor. Suddenly stopping this medicine can lead to symptoms such as fever, confusion, mental status changes, and muscle stiffness.

Missed dose: If you miss a dose of amantadine, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose according to your regular dosing schedule. Do not take extra medicine to make up for missed doses. If you have not taken the extended-release capsules or tablets for several days, call your doctor.

Storage: Store amantadine at room temperature (between 15-30° C or 59-86° F) away from moisture, heat, and direct light in a tightly closed container. Do not store medications in the bathroom where they can be exposed to moisture and heat. Keep all medications safely out of reach of children and pets.

Unused medicine: Unused amantadine should be disposed of in a way that children, other people, and pets cannot get to them. Do not throw amantadine in the trash or flush it down the toilet. The best way to dispose of expired or unneeded amantadine is through a drug take-back program. Learn more about proper medication disposal. 

NOTE: This medication guide is a summary and may not contain all possible drug information on amantadine. The information contained here may not be up-to-date. This sheet is for information purposes only. If you have questions about amantadine, talk to your doctor or pharmacist for medical advice.

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